We noticed that Acr- and Cro-dG adducts are primarily shaped from omega-3, and the adducts derived from longer chain enals, equivalent to HNE, have been detected solely from omega-6 fatty acids.
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Thus, whereas high dietary consumption of n-6 polyunsaturated fatty acids (PUFA), primarily LA, and saturated fats has tumor-enhancing effects, long chain n-3 PUFA, CLA and GLA have inhibitory results.
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